Inhibition by genistein of the lipopolysaccharide-induced down-regulation of programmed cell death 4 in RAW 264.7 mouse macrophages.
نویسندگان
چکیده
Programmed cell death 4 (Pdcd4), a novel tumor suppressor, has recently emerged as an anti-inflammatory protein. We assessed in the present study the effects of 18 different food factors with anti-inflammatory activity on the lipopolysaccharide-induced down-regulation of pdcd4 mRNA expression in mouse RAW 264.7 macrophages. Genistein, a soy isoflavone, significantly inhibited pdcd4 down-regulation.
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 74 5 شماره
صفحات -
تاریخ انتشار 2010